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Rearrangement of immunoglobulin heavy chain genes during B-lymphocyte development as revealed by studies of mouse plasmacytoma cells

We have used Southern's blotting technique to determine the extent to which the genes encoding the constant (C) regions of μ, α, γ(1), and γ(2b) immunoglobulin heavy (H) chains are altered in number and context from their germline (embryo) state in a series of 14 plasmacytomas expressing variou...

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Detalhes bibliográficos
Principais autores: Coleclough, C., Cooper, D., Perry, R. P.
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC348507/
https://ncbi.nlm.nih.gov/pubmed/6769113
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