Genome-Wide Association Study to Identify the Genetic Determinants of Otitis Media Susceptibility in Childhood

BACKGROUND: Otitis media (OM) is a common childhood disease characterised by middle ear inflammation and effusion. Susceptibility to recurrent acute OM (rAOM; ≥3 episodes of AOM in 6 months) and chronic OM with effusion (COME; MEE ≥3 months) is 40–70% heritable. Few underlying genes have been identi...

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Autors principals: Rye, Marie S., Warrington, Nicole M., Scaman, Elizabeth S. H., Vijayasekaran, Shyan, Coates, Harvey L., Anderson, Denise, Pennell, Craig E., Blackwell, Jenefer M., Jamieson, Sarra E.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485007/
https://ncbi.nlm.nih.gov/pubmed/23133572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048215
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