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Zebrafish homologs of genes within 16p11.2, a genomic region associated with brain disorders, are active during brain development, and include two deletion dosage sensor genes

Deletion or duplication of one copy of the human 16p11.2 interval is tightly associated with impaired brain function, including autism spectrum disorders (ASDs), intellectual disability disorder (IDD) and other phenotypes, indicating the importance of gene dosage in this copy number variant region (...

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Bibliografske podrobnosti
Main Authors: Blaker-Lee, Alicia, Gupta, Sunny, McCammon, Jasmine M., De Rienzo, Gianluca, Sive, Hazel
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Limited 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484866/
https://ncbi.nlm.nih.gov/pubmed/22566537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.009944
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