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Identification of compounds with anti-convulsant properties in a zebrafish model of epileptic seizures

The availability of animal models of epileptic seizures provides opportunities to identify novel anticonvulsants for the treatment of people with epilepsy. We found that exposure of 2-day-old zebrafish embryos to the convulsant agent pentylenetetrazole (PTZ) rapidly induces the expression of synapti...

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Detalhes bibliográficos
Main Authors: Baxendale, Sarah, Holdsworth, Celia J., Meza Santoscoy, Paola L., Harrison, Michael R. M., Fox, James, Parkin, Caroline A., Ingham, Philip W., Cunliffe, Vincent T.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484860/
https://ncbi.nlm.nih.gov/pubmed/22730455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.010090
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