The Nonnucleoside Reverse Transcription Inhibitor MIV-160 Delivered from an Intravaginal Ring, But Not from a Carrageenan Gel, Protects Against Simian/Human Immunodeficiency Virus-RT Infection

We previously showed that a carrageenan (CG) gel containing 50 μM MIV-150 (MIV-150/CG) reduced vaginal simian/human immunodeficiency virus (SHIV)-RT infection of macaques (56%, p>0.05) when administered daily for 2 weeks with the last dose given 8 h before challenge. Additionally, when 100 mg of...

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Detalhes bibliográficos
Main Authors: Aravantinou, Meropi, Singer, Rachel, Derby, Nina, Calenda, Giulia, Mawson, Paul, Abraham, Ciby J., Menon, Radhika, Seidor, Samantha, Goldman, Daniel, Kenney, Jessica, Villegas, Guillermo, Gettie, Agegnehu, Blanchard, James, Lifson, Jeffrey D., Piatak, Michael, Fernández-Romero, José A., Zydowsky, Thomas M., Teleshova, Natalia, Robbiani, Melissa
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Animal Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484820/
https://ncbi.nlm.nih.gov/pubmed/22816564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2012.0080
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