TNF signaling drives myeloid-derived suppressor cell accumulation

TNF, an inflammatory cytokine that is enriched in the tumor microenvironment, promotes tumor growth and subverts innate immune responses to cancer cells. We previously reported that tumors implanted in TNF receptor–deficient (Tnfr(–/–)) mice are spontaneously rejected; however, the molecular mechani...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhao, Xueqiang, Rong, Lijie, Zhao, Xiaopu, Li, Xiao, Liu, Xiaoman, Deng, Jingjing, Wu, Hao, Xu, Xia, Erben, Ulrike, Wu, Peihua, Syrbe, Uta, Sieper, Joachim, Qin, Zhihai
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484453/
https://ncbi.nlm.nih.gov/pubmed/23064360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64115
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