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Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes
Diabetic cardiomyopathy (DbCM), which consists of cardiac hypertrophy and failure in the absence of traditional risk factors, is a major contributor to increased heart failure risk in type 2 diabetes patients. In rodent models of DbCM, cardiac hypertrophy and dysfunction have been shown to depend up...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3484448/ https://ncbi.nlm.nih.gov/pubmed/23023704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63888 |
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