Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes

Diabetic cardiomyopathy (DbCM), which consists of cardiac hypertrophy and failure in the absence of traditional risk factors, is a major contributor to increased heart failure risk in type 2 diabetes patients. In rodent models of DbCM, cardiac hypertrophy and dysfunction have been shown to depend up...

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Detalhes bibliográficos
Main Authors: Russo, Sarah Brice, Baicu, Catalin F., Van Laer, An, Geng, Tuoyu, Kasiganesan, Harinath, Zile, Michael R., Cowart, L. Ashley
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484448/
https://ncbi.nlm.nih.gov/pubmed/23023704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63888
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