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Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes

Intrahepatic cholangiocarcinoma (ICC) is the second most common primary malignancy in the liver. ICC has been classified as a malignant tumor arising from cholangiocytes; however, the co-occurrence of ICC and viral hepatitis suggests that ICC originates in hepatocytes. In order to determine the cell...

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Detalles Bibliográficos
Main Authors: Sekiya, Sayaka, Suzuki, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484442/
https://ncbi.nlm.nih.gov/pubmed/23023701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63065
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