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Chronic vascular risk factors (cholesterol, homocysteine, ethanol) impair spatial memory, decline cholinergic neurons and induce blood–brain barrier leakage in rats in vivo

Epidemiological studies show that vascular risk factors (e.g. atherosclerosis, diabetes, homocysteine, hypertension or cholesterol) may play a role in the development of Alzheimer's disease. Animal models may help to discover the role of vascular risk factors on cognition. In the present projec...

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Detalhes bibliográficos
Main Authors: Ehrlich, Daniela, Humpel, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484398/
https://ncbi.nlm.nih.gov/pubmed/22819352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2012.07.002
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