Pathological Role of Serum- and Glucocorticoid-Regulated Kinase 1 in Adverse Ventricular Remodeling

BACKGROUND: Heart failure is a growing cause of morbidity and mortality. Cardiac PI3-kinase signaling promotes cardiomyocyte survival and function but is paradoxically activated in heart failure, suggesting chronic activation of this pathway may become maladaptive. Here we investigated the downstrea...

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Main Authors: Das, Saumya, Aiba, Takeshi, Rosenberg, Michael, Hessler, Katherine, Xiao, Chunyang, Quintero, Pablo A., Ottaviano, Filomena G., Knight, Ashley C., Graham, Evan L., Boström, Pontus, Morissette, Michael R., del Monte, Federica, Begley, Michael J., Cantley, Lewis C., Ellinor, Patrick T., Tomaselli, Gordon F., Rosenzweig, Anthony
格式: Artigo
語言:Inglês
出版: 2012
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484211/
https://ncbi.nlm.nih.gov/pubmed/23019294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.112.115592
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