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Posttranslational modification of elongation factor 2 in diphtheria-toxin-resistant mutants of CHO-K1 cells.

We have identified two types of mutants of Chinese hamster ovary cells in which the unique ADP-ribose attachment site in elongation factor 2 (EF-2) is altered, thereby rendering them resistant to diphtheria and Pseudomonas toxins (TOXR). The first is mutant in the gene for EF-2 and possesses a perma...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Moehring, J M, Moehring, T J, Danley, D E
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1980
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348413/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6928655/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.2.1010
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