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SLAC, a complex between Sla1 and Las17, regulates actin polymerization during clathrin-mediated endocytosis
During clathrin-mediated endocytosis, branched actin polymerization nucleated by the Arp2/3 complex provides force needed to drive vesicle internalization. Las17 (yeast WASp) is the strongest activator of the Arp2/3 complex in yeast cells; it is not autoinhibited and arrives to endocytic sites 20 s...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The American Society for Cell Biology
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3484103/ https://ncbi.nlm.nih.gov/pubmed/22973053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-12-1022 |
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