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Comparative multi-goal tradeoffs in systems engineering of microbial metabolism

BACKGROUND: Metabolic engineering design methodology has evolved from using pathway-centric, random and empirical-based methods to using systems-wide, rational and integrated computational and experimental approaches. Persistent during these advances has been the desire to develop design strategies...

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Detalhes bibliográficos
Main Authors: Byrne, David, Dumitriu, Alexandra, Segrè, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484036/
https://ncbi.nlm.nih.gov/pubmed/23009214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-127
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