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Large Oncosomes in Human Prostate Cancer Tissues and in the Circulation of Mice with Metastatic Disease
Oncosomes are tumor-derived microvesicles that transmit signaling complexes between cell and tissue compartments. Herein, we show that amoeboid tumor cells export large (1- to 10-μm diameter) vesicles, derived from bulky cellular protrusions, that contain metalloproteinases, RNA, caveolin-1, and the...
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3483805/ https://ncbi.nlm.nih.gov/pubmed/23022210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.07.030 |
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