Large Oncosomes in Human Prostate Cancer Tissues and in the Circulation of Mice with Metastatic Disease

Oncosomes are tumor-derived microvesicles that transmit signaling complexes between cell and tissue compartments. Herein, we show that amoeboid tumor cells export large (1- to 10-μm diameter) vesicles, derived from bulky cellular protrusions, that contain metalloproteinases, RNA, caveolin-1, and the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Di Vizio, Dolores, Morello, Matteo, Dudley, Andrew C., Schow, Peter W., Adam, Rosalyn M., Morley, Samantha, Mulholland, David, Rotinen, Mirja, Hager, Martin H., Insabato, Luigi, Moses, Marsha A., Demichelis, Francesca, Lisanti, Michael P., Wu, Hong, Klagsbrun, Michael, Bhowmick, Neil A., Rubin, Mark A., D'Souza-Schorey, Crislyn, Freeman, Michael R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Investigative Pathology 2012
Pynciau:
Regular Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483805/
https://ncbi.nlm.nih.gov/pubmed/23022210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.07.030
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg