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Evidence for involvement of proline cis-trans isomerization in the slow unfolding reaction of RNase A.

The three exposed tyrosines of RNase A have been converted to nitrotyrosines by reaction with tetranitromethane, and the changes in the ionization properties of these nitrotyrosines have been used to follow the kinetics of unfolding of the nitrated protein. It is found that the nitrotyrosines not on...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Autor principal: Garel, J R
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348367/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6928678/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.2.795
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