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Accurate DNA Fragment Sizing by Capillary Electrophoresis with Laser-Induced Fluorescence Array for Detection of Sequence Specificity of DNA Damage

Cancer has been linked to mutations within specific codons in genes that code for critical biomolecules such as tumor suppressor proteins (e.g., p53). Activated metabolites like benzo[a]pyrenediol epoxide act on preferred nucleotide sequences of DNA, and such mutations have been identified in cancer...

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Main Authors: Fundador, Erwin V., Choudhary, Dharamainder, Schenkman, John B., Rusling, James F.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483637/
https://ncbi.nlm.nih.gov/pubmed/18266391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac702265b
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