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A miRNA-regulatory network explains how dysregulated miRNAs perturb oncogenic processes across diverse cancers

Genes regulated by the same miRNA can be discovered by virtue of their coexpression at the transcriptional level and the presence of a conserved miRNA-binding site in their 3′ UTRs. Using this principle we have integrated the three best performing and complementary algorithms into a framework for in...

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Detalhes bibliográficos
Main Authors: Plaisier, Christopher L., Pan, Min, Baliga, Nitin S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483559/
https://ncbi.nlm.nih.gov/pubmed/22745231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.133991.111
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