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Direct Regulation of GTP Homeostasis by (p)ppGpp: A Critical Component of Viability and Stress Resistance

Cells constantly adjust their metabolism in response to environmental conditions, yet major mechanisms underlying survival remain poorly understood. We discover a post-transcriptional mechanism that integrates starvation response with GTP homeostasis to allow survival, enacted by the nucleotide (p)p...

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Detalhes bibliográficos
Main Authors: Kriel, Allison, Bittner, Alycia N., Kim, Sok Ho, Liu, Kuanqing, Tehranchi, Ashley K., Zou, Winnie Y., Rendon, Samantha, Chen, Rui, Tu, Benjamin P., Wang, Jue D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483369/
https://ncbi.nlm.nih.gov/pubmed/22981860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.08.009
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