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Generation of oncogenic mouse type C viruses: in vitro selection of carcinoma-inducing variants.

Type C retroviruses are endogenous in most vertebrate species. These viruses generally are of low pathogenicity in their natural hosts. Variants that contain cell-derived transforming genes have been isolated infrequently in the past upon continued passage in vivo. We report here a procedure that al...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Rapp, U R, Todaro, G J
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1980
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348327/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6244570/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.1.624
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