Over-Expression of DSCR1 Protects against Post-Ischemic Neuronal Injury

BACKGROUND AND PURPOSE: The Down syndrome candidate region 1 (DSCR1) gene is located on human chromosome 21 and its protein is over-expressed in brains of Down syndrome individuals. DSCR1 can modulate the activity of calcineurin, a phosphatase abundant in the brain, but its influence on stroke outco...

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Main Authors: Brait, Vanessa H., Martin, Katherine R., Corlett, Alicia, Broughton, Brad R. S., Kim, Hyun Ah, Thundyil, John, Drummond, Grant R., Arumugam, Thiruma V., Pritchard, Melanie A., Sobey, Christopher G.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483156/
https://ncbi.nlm.nih.gov/pubmed/23144708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047841
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