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Computational and Experimental Analyses Reveal the Essential Roles of Inter-domain Linkers in the Biological Function of Chemotaxis Histidine Kinase CheA

A two-component signal transduction pathway underlies the phenomenon of bacterial chemotaxis that allows bacteria to modulate their swimming behavior in response to environmental stimuli. The dimeric five-domain histidine kinase, CheA, plays a central role in the pathway, converting sensory signals...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Xiqing, Wu, Chun, Vu, Anh, Shea, Joan-Emma, Dahlquist, Frederick W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483030/
https://ncbi.nlm.nih.gov/pubmed/22992224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3056694
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