Relationships of Coronary Heart Disease with 27-Hydroxycholesterol, Low Density Lipoprotein Cholesterol, and Menopausal Hormone Therapy

BACKGROUND: Menopausal hormone therapy (MHT) increases risk of coronary heart disease (CHD) in older women with elevated low-density lipoprotein (LDLC) levels. The endogenous estrogen receptor antagonist 27-hydroxycholesterol (27OHC) is correlated with LDLC levels and may block beneficial effects of...

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Main Authors: Rossouw, Jacques E., Prentice, Ross L., Manson, JoAnn E., Aragaki, Aaron K., Hsia, Judith, Martin, Lisa W., Kuller, Lewis, Johnson, Karen C., Eaton, Charles, Jackson, Rebecca, Trevisan, Maurizio, Allison, Matthew, Hoogeveen, Ron C.
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482942/
https://ncbi.nlm.nih.gov/pubmed/22932256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.112.103218
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