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Synthesis and Secretion of Renin in Mice with Induced Genetic Mutations

The juxtaglomerular (JG) cell product renin is rate-limiting in the generation of the bioactive octapeptide angiotensin II. Rates of synthesis and secretion of the aspartyl protease renin by JG cells are controlled by multiple afferent and efferent pathways originating in the CNS, cardiovascular sys...

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Bibliographic Details
Main Authors: Schnermann, Jurgen, Briggs, Josephine P.
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482822/
https://ncbi.nlm.nih.gov/pubmed/22258323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2011.451
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