Isolation of human MHC class II-restricted T cell receptors from the autologous T-cell repertoire with potent anti-leukaemic reactivity

Adoptive transfer of T cells genetically modified with tumour-specific T-cell receptors (TCR) is a promising novel approach in the treatment of cancer. We have previously isolated an allorestricted MHC class I-restricted TCR with specificity for Formin-like protein 1 (FMNL1) with potent activity aga...

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Detalhes bibliográficos
Main Authors: Weigand, Luise U, Liang, Xiaoling, Schmied, Sabine, Mall, Sabine, Klar, Richard, Stötzer, Oliver J, Salat, Christoph, Götze, Katharina, Mautner, Josef, Peschel, Christian, Krackhardt, Angela M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482680/
https://ncbi.nlm.nih.gov/pubmed/23025755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12000
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