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Systemic mast cell activation disease: the role of molecular genetic alterations in pathogenesis, heritability and diagnostics

Despite increasing understanding of its pathophysiology, the aetiology of systemic mast cell activation disease (MCAD) remains largely unknown. Research has shown that somatic mutations in kinases are necessary for the establishment of a clonal mast cell population, in particular mutations in the ty...

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Detalhes bibliográficos
Main Authors: Haenisch, Britta, Nöthen, Markus M, Molderings, Gerhard J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482677/
https://ncbi.nlm.nih.gov/pubmed/22957768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2012.03627.x
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