TWIST1 associates with NF-κB subunit RELA via carboxyl-terminal WR domain to promote cell autonomous invasion through IL8 production

BACKGROUND: Metastasis is the primary cause of death for cancer patients. TWIST1, an evolutionarily conserved basic helix-loop-helix (bHLH) transcription factor, is a strong promoter of metastatic spread and its expression is elevated in many advanced human carcinomas. However, the molecular events...

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Detalhes bibliográficos
Main Authors: Li, Shan, Kendall, Stephen E, Raices, Raquel, Finlay, James, Covarrubias, Maricela, Liu, Zheng, Lowe, Gina, Lin, Yu-Huey, Teh, Yuan Han, Leigh, Victoria, Dhillon, Simi, Flanagan, Steven, Aboody, Karen S, Glackin, Carlotta A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482588/
https://ncbi.nlm.nih.gov/pubmed/22891766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-10-73
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