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Vitamin D and the Human Antimicrobial Peptide LL-37 Enhance Group A Streptococcus Resistance to Killing by Human Cells

The CsrRS two-component regulatory system of group A Streptococcus (GAS; Streptococcus pyogenes) responds to subinhibitory concentrations of the human antimicrobial peptide LL-37. LL-37 signaling through CsrRS results in upregulation of genes that direct synthesis of virulence factors, including the...

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Autori principali: Love, John F., Tran-Winkler, Hien J., Wessels, Michael R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482505/
https://ncbi.nlm.nih.gov/pubmed/23093388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00394-12
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