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Engineered Synthetic Polymer Nanoparticles as IgG Affinity Ligands

A process for the preparation of an abiotic protein affinity ligand is described. The affinity ligand, a synthetic polymer hydrogel nanoparticle (NP), is formulated with functional groups complementary to the surface presentation of the target protein. An iterative process is used to improve affinit...

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Bibliografiske detaljer
Main Authors: Lee, Shih-Hui, Hoshino, Yu, Randall, Arlo, Zeng, Zhiyang, Baldi, Piere, Doong, Ruey-an, Shea, Kenneth. J.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482410/
https://ncbi.nlm.nih.gov/pubmed/22924890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja303612d
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