Normal ageing is associated with an increase in Th2 cells, MCP-1 (CCL1) and RANTES (CCL5), with differences in sCD40L and PDGF-AA between sexes

We have observed T helper type 2 (Th2) polarization of systemic immunity in patients with metastatic malignant melanoma. We hypothesized that similar changes in systemic immunity occur with ageing and may be permissive for the development of melanoma. We analysed the peripheral blood of 389 healthy...

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Hauptverfasser: Mansfield, A S, Nevala, W K, Dronca, R S, Leontovich, A A, Shuster, L, Markovic, S N
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2012
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482365/
https://ncbi.nlm.nih.gov/pubmed/23039889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2012.04644.x
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