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The Fraction Dose Absorbed, in Humans, and High Jejunal Human Permeability Relationship

The drug intestinal permeability (P(eff)) measure has been widely used as one of the main factors governing both the rate and/or extent of drug absorption (F(abs)) in humans following oral administration. In this communication we emphasize the complexity behind and the care that must be taken with t...

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Bibliografiske detaljer
Main Authors: Dahan, Arik, Lennernäs, Hans, Amidon, Gordon L.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482341/
https://ncbi.nlm.nih.gov/pubmed/22524707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300140h
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