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The Fraction Dose Absorbed, in Humans, and High Jejunal Human Permeability Relationship

The drug intestinal permeability (P(eff)) measure has been widely used as one of the main factors governing both the rate and/or extent of drug absorption (F(abs)) in humans following oral administration. In this communication we emphasize the complexity behind and the care that must be taken with t...

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Detalhes bibliográficos
Main Authors: Dahan, Arik, Lennernäs, Hans, Amidon, Gordon L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482341/
https://ncbi.nlm.nih.gov/pubmed/22524707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300140h
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