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Antisickling activity of amino acid benzyl esters.

The sickling of homozygous sickel cells upon deoxygenation is inhibited in the presence of 3 mM L-phenylalanine benzyl ester (Phe-OBzl) or benzyl esters of other aromatic or hydrophobic amino acids. Phe-OBzl was found to permeate into erythrocytes rapidly, and the deoxygenated cells maintained consi...

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Detalhes bibliográficos
Main Authors: Gorecki, M, Acquaye, C T, Wilchek, M, Votano, J R, Rich, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC348232/
https://ncbi.nlm.nih.gov/pubmed/6928612
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