A Genome-wide Functional Screen Shows MAGI-1 Is an L1CAM-Dependent Stabilizer of Apical Junctions in C. elegans

BACKGROUND: In multicellular organisms, cell-cell junctions are involved in many aspects of tissue morphogenesis. α-catenin links the cadherin-catenin complex (CCC) to the actin cytoskeleton, stabilizing cadherin-dependent adhesions. RESULTS: To identify modulators of cadherin-based cell adhesion, w...

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Detalhes bibliográficos
Main Authors: Lynch, Allison M., Grana, Theresa, Cox, Elizabeth, Couthier, Annabelle, Cameron, Michel, Chin-Sang, Ian, Pettitt, Jonathan, Hardin, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482306/
https://ncbi.nlm.nih.gov/pubmed/22981773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.08.024
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