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Biomimetic perfusion and electrical stimulation applied in concert improved the assembly of engineered cardiac tissue

Maintenance of normal myocardial function depends intimately on synchronous tissue contraction driven by electrical activation and on adequate nutrient perfusion in support thereof. Bioreactors have been used to mimic aspects of these factors in vitro to engineer cardiac tissue, but due to design li...

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Bibliographic Details
Main Authors: Maidhof, Robert, Tandon, Nina, Lee, Eun Jung, Luo, Jianwen, Duan, Yi, Yeager, Keith, Konofagou, Elisa, Vunjak-Novakovic, Gordana
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482289/
https://ncbi.nlm.nih.gov/pubmed/22170772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/term.525
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