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Loss of sfrp1 promotes ductal branching in the murine mammary gland
BACKGROUND: Secreted frizzled-related proteins (SFRPs) are a family of proteins that block the Wnt signaling pathway and loss of SFRP1 expression is found in breast cancer along with a multitude of other human cancers. Activated Wnt signaling leads to inappropriate mammary gland development and mamm...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3482146/ https://ncbi.nlm.nih.gov/pubmed/22928951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-12-25 |
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