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Activation of pyruvate dehydrogenase by direct addition of insulin to an isolated plasma membrane/mitochondria mixture: Evidence for generation of insulin's second messenger in a subcellular system

The addition of insulin to a mixture of plasma membrane and mitochondrial fractions from rat adipocytes results in a decrease in the phosphorylation of a mitochondrial protein identified as the α subunit of pyruvate dehydrogenase [pyruvate:lipoamide oxidoreductase (decarboxylating and acceptor-acety...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Seals, Jonathan R., Jarett, Leonard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348211/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6987660/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.1.77
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