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Safe Genetic Modification of Cardiac Stem Cells Using a Site-Specific Integration Technique

BACKGROUND: Human cardiac progenitor cells (hCPCs) are a promising cell source for regenerative repair after myocardial infarction. Exploitation of their full therapeutic potential may require stable genetic modification of the cells ex vivo. Safe genetic engineering of stem cells, using facile meth...

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Autores principales: Lan, Feng, Liu, Junwei, Narsinh, Kazim H., Hu, Shijun, Han, Leng, Lee, Andrew S., Karow, Marisa, Nguyen, Patricia K., Nag, Divya, Calos, Michele P., Robbins, Robert C., Wu, Joseph C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481839/
https://ncbi.nlm.nih.gov/pubmed/22965984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.111.084913
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