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The effect of remodelling and contractility of the actin cytoskeleton on the shear resistance of single cells: a computational and experimental investigation

The biomechanisms that govern the response of chondrocytes to mechanical stimuli are poorly understood. In this study, a series of in vitro tests are performed, in which single chondrocytes are subjected to shear deformation by a horizontally moving probe. Dramatically different probe force–indentat...

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Bibliografiske detaljer
Main Authors: Dowling, Enda P., Ronan, William, Ofek, Gidon, Deshpande, Vikram S., McMeeking, Robert M., Athanasiou, Kyriacos A., McGarry, J. Patrick
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481572/
https://ncbi.nlm.nih.gov/pubmed/22809850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2012.0428
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