Identical RNA-Protein Interactions in Vivo and in Vitro and a Scheme of Folding the Newly Synthesized Proteins by Ribosomes

A distinct three-dimensional shape of rRNA inside the ribosome is required for the peptidyl transfer activity of its peptidyltransferase center (PTC). In contrast, even the in vitro transcribed PTC RNA interacts with unfolded protein(s) at about five sites to let them attain their native states. We...

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Detalhes bibliográficos
Main Authors: Das, Debasis, Samanta, Dibyendu, Hasan, Salman, Das, Anindita, Bhattacharya, Arpita, Dasgupta, Santanu, Chakrabarti, Abhijit, Ghorai, Pradip, Das Gupta, Chanchal
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481345/
https://ncbi.nlm.nih.gov/pubmed/22932895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.396127
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