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New Insights into the Mechanism of Initial Transcription: THE T7 RNA POLYMERASE MUTANT P266L TRANSITIONS TO ELONGATION AT LONGER RNA LENGTHS THAN WILD TYPE

RNA polymerases undergo substantial structural and functional changes in transitioning from sequence-specific initial transcription to stable and relatively sequence-independent elongation. Initially, transcribing complexes are characteristically unstable, yielding short abortive products on the pat...

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Detalhes bibliográficos
Main Authors: Ramírez-Tapia, Luis E., Martin, Craig T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481332/
https://ncbi.nlm.nih.gov/pubmed/22923611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.370643
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