Increased Phosphoenolpyruvate Carboxykinase Gene Expression and Steatosis during Hepatitis C Virus Subgenome Replication: ROLE OF NONSTRUCTURAL COMPONENT 5A AND CCAAT/ENHANCER-BINDING PROTEIN β

Chronic hepatitis C virus (HCV) infection greatly increases the risk for type 2 diabetes and nonalcoholic steatohepatitis; however, the pathogenic mechanisms remain incompletely understood. Here we report gluconeogenic enzyme phosphoenolpyruvate carboxykinase (PEPCK) transcription and associated tra...

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Hlavní autoři: Qadri, Ishtiaq, Choudhury, Mahua, Rahman, Shaikh Mizanoor, Knotts, Trina A., Janssen, Rachel C., Schaack, Jerome, Iwahashi, Mieko, Puljak, Livia, Simon, Francis R., Kilic, Gordan, Fitz, J. Gregory, Friedman, Jacob E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481331/
https://ncbi.nlm.nih.gov/pubmed/22955269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.384743
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