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A Single Nucleotide Polymorphism in IL28B Affects Viral Evolution of Hepatitis C Quasispecies after Pegylated Interferon and Ribavirin Therapy

Interleukin-28B (IL28B) polymorphisms are associated with viral response to peginterferon and ribavirin in chronic hepatitis C (HCV). Their recognition represents a breakthrough in the understanding of the role of the host in viral eradication. How these polymorphisms determine viral eradication is...

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Detalhes bibliográficos
Main Authors: Yuan, Hejun, Adams-Huet, Beverley, Petersen, Tianna, Attar, Nahid, Lee, William M., Jain, Mamta K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481197/
https://ncbi.nlm.nih.gov/pubmed/23080496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmv.23407
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