The inhibitory effect of S-nitrosoglutathione on blood-brain barrier disruption and peroxynitrite formation in a rat model of experimental stroke

The hallmark of stroke injury is endothelial dysfunction leading to blood brain barrier (BBB) leakage and edema. Among the causative factors of BBB disruption are accelerating peroxynitrite formation and the resultant decreased bioavailability of nitric oxide (NO). S-nitrosoglutathione (GSNO), an S-...

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Autori principali: Khan, Mushfiquddin, Dhammu, Tajinder S, Sakakima, Harutoshi, Shunmugavel, Anadakumar, Gilg, Anne G, Singh, Avtar K., Singh, Inderjit
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481195/
https://ncbi.nlm.nih.gov/pubmed/23050646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2012.07947.x
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