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Radiation as an immunological adjuvant: current evidence on dose and fractionation

Ionizing radiation to a cancer site has the ability to convert the irradiated tumor in an immunogenic hub. However, radiation is a complex modifier of the tumor microenvironment and, by itself, is seldom sufficient to induce a therapeutically significant anti-tumor immune response, since it can also...

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Detalhes bibliográficos
Main Authors: Demaria, Sandra, Formenti, Silvia C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481113/
https://ncbi.nlm.nih.gov/pubmed/23112958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2012.00153
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