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Divergence of sperm and leukocyte age-dependent telomere dynamics: implications for male-driven evolution of telomere length in humans

Telomere length (TL) dynamics in vivo are defined by TL and its age-dependent change, brought about by cell replication. Leukocyte TL (LTL), which reflects TL in hematopoietic stem cells (HSCs), becomes shorter with age. In contrast, sperm TL, which reflects TL in the male germ cells, becomes longer...

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Detalhes bibliográficos
Main Authors: Aston, Kenneth I., Hunt, Steven C., Susser, Ezra, Kimura, Masayuki, Factor-Litvak, Pam, Carrell, Douglas, Aviv, Abraham
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480822/
https://ncbi.nlm.nih.gov/pubmed/22782639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gas028
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