Divergence of sperm and leukocyte age-dependent telomere dynamics: implications for male-driven evolution of telomere length in humans

Telomere length (TL) dynamics in vivo are defined by TL and its age-dependent change, brought about by cell replication. Leukocyte TL (LTL), which reflects TL in hematopoietic stem cells (HSCs), becomes shorter with age. In contrast, sperm TL, which reflects TL in the male germ cells, becomes longer...

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Bibliographic Details
Main Authors: Aston, Kenneth I., Hunt, Steven C., Susser, Ezra, Kimura, Masayuki, Factor-Litvak, Pam, Carrell, Douglas, Aviv, Abraham
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480822/
https://ncbi.nlm.nih.gov/pubmed/22782639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gas028
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