Betulinic acid inhibits superoxide anion-mediated impairment of endothelium-dependent relaxation in rat aortas

OBJECTIVES: To investigate the protective effect of betulinic acid (BA) on endothelium-dependent relaxation (EDR) in rat aortas exposed to pyrogallol-produced superoxide anion and its underlying mechanism. MATERIALS AND METHODS: The thoracic aorta of male Sprague-Dawley rats was isolated to mount in...

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Bibliographic Details
Main Authors: Qian, Ling-Bo, Fu, Jia-Yin, Cai, Xin, Xia, Man-Li
Format: Artigo
Language:Inglês
Published: Medknow Publications & Media Pvt Ltd 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480790/
https://ncbi.nlm.nih.gov/pubmed/23112419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0253-7613.100382
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