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Identification of the Binding and Inhibition Sites in the Calmodulin Molecule for Ophiobolin A by Site-Directed Mutagenesis

Ophiobolin A, a fungal toxin that affects maize and rice, has previously been shown to inhibit calmodulin by reacting with the lysine (Lys) residues in the calmodulin. In the present study we mutated Lys-75, Lys-77, and Lys-148 in the calmodulin molecule by site-directed mutagenesis, either by delet...

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Autori principali: Kong Au, Tai, Chow Leung, Pak
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Plant Physiologists 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC34807/
https://ncbi.nlm.nih.gov/pubmed/9808741
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