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Mechanistic modeling of aberrant energy metabolism in human disease

Dysfunction in energy metabolism—including in pathways localized to the mitochondria—has been implicated in the pathogenesis of a wide array of disorders, ranging from cancer to neurodegenerative diseases to type II diabetes. The inherent complexities of energy and mitochondrial metabolism present a...

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Detalles Bibliográficos
Main Authors: Sangar, Vineet, Eddy, James A., Simeonidis, Evangelos, Price, Nathan D.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480659/
https://ncbi.nlm.nih.gov/pubmed/23112774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00404
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