Phosphatidylethanolamine and Cardiolipin Differentially Affect the Stability of Mitochondrial Respiratory Chain Supercomplexes

The mitochondrial inner membrane contains two non-bilayer‐forming phospholipids, phosphatidylethanolamine (PE) and cardiolipin (CL). Lack of CL leads to destabilization of respiratory chain supercomplexes, a reduced activity of cytochrome c oxidase, and a reduced inner membrane potential Δψ. Althoug...

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Detalhes bibliográficos
Main Authors: Böttinger, Lena, Horvath, Susanne E., Kleinschroth, Thomas, Hunte, Carola, Daum, Günther, Pfanner, Nikolaus, Becker, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
Assuntos:
Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480645/
https://ncbi.nlm.nih.gov/pubmed/22971339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.09.001
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