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Simple model for the study of Pseudomonas aeruginosa infections in leukopenic mice.

A simple, reproducible model of fatal Pseudomonas aeruginosa sepsis in mice during immunosuppression was developed. Mice were rendered leukopenic (less than or equal to 800 leukocytes per mm3 of blood) for a period of 5 days by multiple injections of cyclophosphamide. Mice were challenged at the ons...

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Bibliografiske detaljer
Main Authors: Cryz, S J, Fürer, E, Germanier, R
Format: Artigo
Sprog:Inglês
Udgivet: 1983
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC348064/
https://ncbi.nlm.nih.gov/pubmed/6404816
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