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Phenylalkyl isoselenocyanates vs phenylalkyl isothiocyanates: thiol reactivity and its implications

Phenylalkyl isoselenocyanate (ISC) compounds were recently designed in our laboratory by incorporating the anticancer element selenium into a panel of phenylalkyl isothiocyanates (ITCs), known to have anticancer properties. A structural activity investigation was carried out to compare the ISC and I...

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Detalhes bibliográficos
Main Authors: Crampsie, Melissa A., Pandey, Manoj K., Desai, Dhimant, Spallholz, Julian, Amin, Shantu, Sharma, Arun K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480549/
https://ncbi.nlm.nih.gov/pubmed/22982772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2012.08.022
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